Labelling a unit as seronegative indicates that the unit does not contain antibodies against CMV. The use of CMV negative blood does not entirely eliminate the risk of transfusion transmitted CMV infection because a donor with a recent infection could harbor virus in their plasma or white blood cells even though they test negative for antibodies.
Milestone Store. All blood donors must wear a mask regardless of vaccination status. Oneblood Blog Subscribe to our blog to read inspiring stories and get the latest news. Follow on Twitter.
All Blogs. Oneblood Blog Subscribe to our blog to read inspiring stories and get the latest news Email. Popular Articles. What Makes Blood Types Rare? Products Blood components Modified blood components CMV seronegative components CMV seronegative components A limited number of donors, including new donors and donors previously identified as cytomegalovirus CMV negative are tested for the presence of CMV antibodies. When should I use this modification?
CMV seronegative products should be used for the following clinical indications: Pregnant women regardless of CMV status who require regular elective transfusions during pregnancy but not during delivery ; Recipients of intrauterine transfusions IUT; Neonates up to 28 days post expected date of delivery and Granulocyte transfusions for CMV negative patients.
For this reason, babies needing transfusions as part of their medical care should only receive CMV negative blood from donors who have not been exposed to CMV.
Be a Hero for Babies. If you have O negative, CMV negative blood, your blood donation is urgently needed to help newborns and premature babies. Most children and adults receiving blood transfusions do not need CMV negative blood. However, CMV can cause serious problems for people who have weakened immune systems, affecting the eyes, lungs, nervous system, and gastrointestinal tract.
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